产品货号：
Z35812
中文名称：
MYD88抗体
英文名称：
Anti-MYD88 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MYD88 Antibody |
| 指标别名 | MYD88;MYD88D |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | MYD88 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MyD88 Members of the Toll-like receptor (TLR) family,named for the closely related Toll receptor in Drosophila,play a pivotal role in innate immune responses.TLRs recognize conserved motifs found in various pathogens and mediate defense responses.Triggering of the TLR pathway leads to the activation of NF- Kappa B and subsequent regulation of immune and inflammatory genes. |
| 实际分子量 | 33KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88),is a protein that,in humans,is encoded by the MYD88 gene.MyD88 is a key downstream adapter for most Toll-like receptors(TLRs) and interleukin-1 receptors(IL1Rs).And it is mapped on 3p22.2.MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.Qverexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter.The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP.Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death,and do so in a way that might not compromise tissue repair or host defense against pathogens. |
| Uniprot ID | Q99836 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Flow cytometry (FCM) 1:20 |
相关搜索：MYD88抗体，MYD88单抗，Anti-MYD88 Antibody